Antimicrobial Resistant Streptococcus pneumoniae
نویسندگان
چکیده
منابع مشابه
Drug-resistant Streptococcus pneumoniae.
Streptococcus pneumoniae remains a major cause of infection in both children and adults, annually resulting in significant morbidity and mortality. The past two decades have seen an alarming worldwide increase in the incidence of drug-resistant S. pneumoniae (DRSP). DRSP is now common throughout the United States, and physicians are questioning how best to approach this epidemic. With the intro...
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Streptococcus pneumoniae is a major cause of pneumonia, meningitis, septicemia, acute otitis media, and other serious infections, severely affecting infants, young children, and the elderly. In the past, S. pneumoniae was uniformly susceptible to penicillin, which remained the drug of choice for serious infections. However, since the mid-1960s, resistance to penicillin, which was first reported...
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To the Editor: In recent years, antimicrobial drug resistance in Streptococcus pneumoniae has increased worldwide and is a major health concern. Resistance to β-lac-tams and macrolides, considered to be first-line therapeutic agents, is particularly high in France and many Asian countries (1–3). Resistance to new fluoroquinolones is reported with increasing frequency, which emphasizes the need ...
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To the Editor: In pneumococci, resistance to fluoroquinolones is associated with chromosomal mutations in the quinolone-resistance–determining regions (QRDR) of type II topoiso-merase enzymes, predominantly gyrA and parC. Several mutations have been described in these enzymes, but only a few have been shown by in vitro studies to confer resistance: S81F or Y, C, or I and E85K in gyrA; E474K in ...
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Streptococcus pneumoniae (pneumococcus) remains a major cause of mortality and morbidity at the extremes of age. With increasing antibiotic resistance, its accurate early identification is important for initial management [1]. Its identification in clinical laboratories relies on colony morphology, α-haemolysis on blood agar, and optochin susceptibility. The bile solubility test, although simpl...
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ژورنال
عنوان ژورنال: Journal of Nepal Medical Association
سال: 2010
ISSN: 1815-672X,0028-2715
DOI: 10.31729/jnma.92